Type 1 diabetes is known to affect children and adolescents, which makes it a very difficult disease to diagnose at the initial stages. Recent research now shows people suffering from chronic intestinal worm infection, especially in developing countries, have lower risk of acquiring type 1 diabetes. Patients often buy Canadian drugs for long-term treatment of the incurable lifestyle ailment. The breakthrough study may actually help reduce number of patients likely to suffer from the disease.
The human body affected by type 1 diabetes stops producing insulin needed to convert sugar and other foods into energy. Researchers based at New Jersey Medical School analyzed several mice cases with the aim of finding out why percentage of type I is lower than type 2 diabetes in developing countries.
Children and adolescents in the United States are increasingly suffering from both forms of the disease. Statistics show prevalence exists at 23% for type 1 and 21% for type 2diabetes. It was therefore important to study why living conditions made considerable difference in reducing number of cases in other countries.
Developing countries find it difficult to sustain hygienic conditions. People are therefore susceptible to chronic intestinal worm infections. Parasites find their way into the intestines through uncooked food or through hands and feet coming in contact with impurities. Water is sometimes contaminated leading to infestation of larva and parasites.
Though intestinal infection can cause severe problems like diarrhea, inflammation, and jaundice, researchers find these parasites are capable of fighting self-destructing T cells capable of causing diabetes and other autoimmune ailments.
Researchers tested mice to identify how exactly worm infection reduces malfunction in T cells. Mice infected with H. polygyrus, an intestinal worm, worked positively on T cells and help produce protein molecules capable of preventing type 1 diabetes. They found interleukin (IL-4 and IL-10) as well as cytokines produced in excess changed pathways within the immune system to prevent the autoimmune disease.
The discovery is vital in helping further studies to be conducted on mice suffering from several other parasites. For example, the H. polygyrus worm was a parasite lodged in the intestines. It was actually changing important body functions increasing resistance against a disease. Researchers have already identified several other worms including the Trichuris Suis capable of producing similar results for other chronic diseases.
Autoimmune diseases are evident on the skin, but several symptoms affect internal tissues leading to complicated illnesses. Diseases like Crohn's disease and multiple sclerosis have always presented difficulty in diagnosis as well as treatment.
People have no option but to control blood sugar with the help of insulin therapy in type 1 diabetes. They often buy Humalog to control symptoms. Many children and adolescents lead normal healthy lives by constantly monitoring blood sugar. However, preventive measures are preferred over traditional treatment options for such incurable diseases. Researchers have now found parasites are capable of reversing several chronic medical conditions.
It is just a matter of time before future studies help develop complete processes capable of preventing type 1 diabetes in highly susceptible cases connected to living conditions or diagnosed with deficiencies in the body. Added information in this direction is also likely to increase awareness about the disease and its prevention.
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